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Written by Stacy Miller
You know how it goes. After a long, hard day, all you want to do is come home and relax with a nice glass of wine or something a bit stronger. It’s common to have a glass or two of alcohol to de-stress, after all, so it couldn’t be that bad, right? Seemingly unrelated, you notice your hormonal symptoms have been getting worse. Your periods are heavier, you have more frequent mood swings, and even your breasts are more tender. You start to wonder, “Could the two be related?” How does alcohol affect hormones in females is an important question, whether you’re in your reproductive years, entering perimenopause, or menopausal. For women, hormonal health is the key to feeling your best at any stage of life. In this article, you’ll find answers backed by science on the link between alcohol and female hormones and what you can do to support healthy hormonal levels. You deserve to feel your best, and we’re here to help you make that happen by giving you the tools to take control of your hormonal health.
- Alcohol has a direct impact on key hormones like estrogen, progesterone, and cortisol.
- Even moderate drinking can worsen perimenopause and PMS symptoms.
- Alcohol initially relaxes you, then disrupts your sleep.
What happens to your hormones after one drink?
You may be surprised to learn that there’s a direct link between alcohol and hormones, since it’s a connection not many people talk about. Alcohol’s impact on the endocrine system and adrenal glands is profound, especially on the HPA axis (hypothalamic-pituitary-adrenal), the body’s central stress response system. While you may feel tired and relaxed at first, after a few hours, the surge in cortisol acts like a shock to the body, often causing anxiety and sleep disruption. But its impact doesn’t stop there.
As an endocrine disruptor, alcohol also impacts key hormones like estrogen and progesterone, since the liver must divert resources away from metabolizing and regulating these hormones to focus on alcohol processing. Proper liver function is essential for hormonal health, which is why overloading it, even with just one drink, can lead to worsening hormone-related symptoms. Let’s explore the connection between alcohol and female hormones further, so you can get a better look into how it affects you in each stage of life.
Alcohol and menstrual cycle
Even a single drink can alter the symptoms you experience during a specific phase of your cycle, often intensifying mood swings and breast tenderness by temporarily spiking estrogen levels. However, regular or heavy drinking poses a greater risk; it can cause chronic hormonal imbalances that lead to anovulation (where the ovaries fail to release an egg). Over time, these disruptions can not only make your cycle unpredictable but also impact overall fertility.
One of the main reasons alcohol can have such a significant impact on your body is its relationship to estrogen. Understanding the connection between alcohol and estrogen can help demystify some of the symptoms you may experience.
When you drink alcohol, it stimulates an enzyme called aromatase, which is responsible for converting androgens into estrogen, this is what we know from animal studies and is not necessarily true for humans. At the same time, it slows the liver’s ability to process the hormone as we discussed above. As a result, many women experience increased estrogen levels, since the body is potentially boosting estrogen production and slowing its breakdown. But why does having higher estrogen levels matter?
To start, higher estrogen levels could cause a thicker uterine lining, which may lead to longer, heavier periods. It can also increase breast tissue density, making your breasts more tender. Estrogen also impacts the mood-regulating areas of your brain, and when the levels are high, you may feel more emotionally sensitive.
Alcohol, anxiety, and sleep disorders
Have you ever had a few drinks and felt sleepy, only to wake up feeling stressed out at 3 a.m.? This experience is often called “hangxiety,” and it’s one of the sneaky side effects of alcohol consumption. How does hangxiety work? When you first start drinking, the alcohol binds with GABA receptors, protein complexes in the brain that slow down your nerve signals. That’s why you have poor reactivity and decision-making abilities when drinking.
When GABA receptors are slowed, you begin feeling relaxed, sleepy, and happy. If alcohol’s impact stopped there, it would be great, but as it’s metabolized, your body overcompensates for the temporary inhibition. As this happens, your deep sleep cycle is disrupted, and you can begin feeling anxious.
Women in perimenopause and menopause can experience heightened negative effects of alcohol. It’s common for sleep issues to be more severe, leading to greater fatigue and irritability. As alcohol impacts the adrenal glands and stress hormones like cortisol, it further disrupts your hormonal balance. It becomes a cycle of alcohol impacting hormone levels, which cause side effects, making it harder to sleep, leading to greater anxiety.
While alcohol can have a more significant effect on women in perimenopause and menopause, its negative impact stretches through all life stages. From your reproductive years to menopause, learning how alcohol impacts your hormones allows you to better understand its effects on your body.
How alcohol impacts hormones at different life stages
| Impact Area | Reproductive years | Perimenopause |
| Estrogen | Alcohol can temporarily increase estrogen, while taken chronically it can disrupt ovulation, lead to irregular cycles and reduce fertility. | Alcohol can trigger more frequent hot flashes since your cooling system is already sensitive due to low estrogen. On the other hand, it may provide some minor benefits for bone health. |
| Progesterone | Alcohol consumption can reduce progesterone, leading to mood swings, anxiety, and worsen PMS symptoms. | During perimenopause progesterone levels decline, alcohol can further speed up aging. |
| Cortisol | Short-term spikes in cortisol may increase stress and fat storage, particularly abdominal. | Chronic elevation of cortisol post-drinking can worsen metabolic changes. |
| Melatonin | Alcohol suppresses melatonin, leading to poor sleep quality. | Already-lower melatonin in menopause means even small amounts of alcohol can severely disrupt rest. |
| Testosterone | Having a drink can cause a slight, temporary spike in testosterone levels, which might unexpectedly increase your libido or worsen acne. | In perimenopause, alcohol-induced testosterone surges occur alongside falling estrogen, which may increase irritability and anger. |
During your reproductive years
Alcohol can affect your ovarian reserve by inducing oxidative stress that damages ovarian cells, possibly leading to reduced egg quality and premature ovarian aging. During the second half of your cycle, alcohol can worsen PMS symptoms.
During the transition to menopause
Perimenopause is a natural life transition where you move away from your reproductive years. During this time, it’s common to experience a range of uncomfortable side effects like vaginal dryness, brain fog, and decreased libido. Alcohol and menopause symptoms often go hand-in-hand, causing or worsening side effects like hot flashes and night sweats. It aggravates these symptoms because it’s a vasodilator, a substance that widens your blood vessels, allowing blood to flow more easily.
Additionally, alcohol can increase mood swings for women in perimenopause and menopause since it disrupts sleep, increases stress hormones, destabilizes your blood sugar, and raises anxiety.
Interestingly, some studies show that postmenopausal women who consume alcohol have better bone density than non-drinkers, likely because alcohol can raise estrogen levels. Despite this, alcohol is not a recommended solution for bone health. Menopause hormone therapy is a far healthier way to protect your bones without the damaging effects alcohol has on the rest of your body.
The hidden impacts: Thyroid, testosterone, and insulin
While alcohol can have numerous effects on your primary reproductive hormones, its impact on secondary hormone levels is equally important.
- Thyroid – Alcohol acts like a toxin to the gland’s cells. Regular drinking can lower the levels of important thyroid hormones (T3 and T4). It also disrupts the “communication line” between your brain and your thyroid, making it harder for your body to maintain a steady metabolism. This can lead to symptoms like fatigue, feeling cold, or brain fog, as your thyroid struggles to keep your body’s energy levels in balance.
- Testosterone – Having a drink can cause a temporary spike in testosterone levels, which might unexpectedly increase libido or worsen hormonal acne.
- Insulin – moderate drinking may help lower fasting insulin and blood sugar levels in people without diabetes. Additionally, alcohol consumption appears to improve insulin sensitivity specifically in women, even though this effect was not seen in everyone. While moderate drinking usually doesn’t lead to weight gain, heavy drinking can certainly increase the risk of obesity. This is due to several factors, including an overall less healthy lifestyle and the way alcohol slows the body’s ability to burn fat.
A practical guide to mindful drinking for hormonal health
While alcohol in excess can cause numerous issues to your hormonal health, there are ways to drink it mindfully. We believe you shouldn’t feel guilty for indulging occasionally, which is why we made this practical guide to drinking with your hormone health in mind.
Tip 1: Know your numbers
Moderation is the key to success in most areas of life, especially when it comes to drinking. Following NHS guidelines for moderate drinking will help you avoid overindulging. Health experts recommend keeping your weekly alcohol intake under 14 units.
Instead of “saving up” your drinks for one night, it is much healthier to distribute them over three days or more. You should also aim for several days each week where you don’t drink at all. Please note that if you are pregnant or trying to get pregnant, the safest approach is to avoid alcohol completely.
Tip 2: Timing is everything
Cycle-syncing your drinking can make all the difference with hormone balancing. It’s best to avoid drinking alcohol in your late luteal phase when your PMS symptoms are the worst. Drinking in the evening can disrupt your sleep, so it’s best to avoid late-night spirits.
Tip 3: Hydrate and nourish
Pairing your alcohol with water will help you avoid dehydration and the dreaded hangover. You can also eat a protein-rich meal beforehand to slow the alcohol absorption.
Tip 4: Choose your drink wisely
The type of alcohol you drink also plays a big role in how it affects your body. Sugary cocktails can have a bigger impact on your blood sugar levels than plain spirits.
How to track your body’s response
When it comes to understanding your body’s responses, tracking is your best friend. Start by keeping a journal or using an app like Hormona to track your cycle, symptoms, and alcohol intake. You may be surprised to discover that one drink the week before your period starts triggers migraines or that wine negatively impacts your sleep. Having this personalized data makes it easier to make choices that work best for you. How does journaling and tracking work? Every day, take a few minutes to write down what you eat and drink in your journal.
You don’t have to change anything; the goal is strictly observation. Using a hormone tracking app like Hormona, you can input any symptoms you’re having, like cramping, headaches, or breast tenderness. For even deeper insight, pairing your tracking with a hormone testing kit can help you better understand what’s happening internally throughout your cycle. At the end of the month, compare your symptoms with what you ate and drank, along with where you were in your menstrual cycle, to determine if any patterns arise. From there, you can make changes to your diet like limiting sugar, avoiding certain types of alcohol, and increasing your vegetable intake.
Hormone balancing is incredibly important to your overall health and wellbeing, and mindful drinking can play a key role in the process. Understanding how the foods and drinks you consume impact your body allows you to make thoughtful choices that help you feel your best.
Hormona is proud to offer scientifically-backed insights and valuable tools that let you take control of your hormonal health. Our hormone tracking app is user-friendly and our extensive blog library provides helpful resources to take the mystery out of how your body functions. Every woman deserves to understand how her body works and the role hormones play; Hormona puts control in your hands so you can better understand your hormonal health and feel your best.
FAQs
Can one night of heavy drinking mess up my hormones?
Yes, even one night of heavy drinking can mess up your hormones by causing fluctuations in cortisol, estrogen, progesterone, and testosterone.
Does quitting alcohol completely reset your hormones?
Quitting alcohol can play a role in resetting your hormones, since it allows them to begin restabilizing to healthy fluctuations. However, there’s numerous factors that go into hormonal balance like lifestyle, exercise, stress management, and diet.
What are the best alcoholic drinks for hormone balance?
There is no good alcoholic drink for hormone balance, however, some spirits have less of a negative affect than others. For example, sugar drinks can spike blood sugar, while dry wines and plain spirits are believed to be less impactful.
How does alcohol affect fertility and trying to conceive?
Alcohol can make it harder to conceive since it’s an endocrine disruptor than can imbalance key reproductive hormones like estrogen and progesterone. Alcohol can also reduce ovarian reserves and cause premature ovarian aging.
Will reducing alcohol help with my menopause-related weight gain?
Yes, since alcohol can make menopausal-related weight gain worse, reducing or stopping consumption may help make losing or maintaining your weight easier.
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Dr Singh is the Medical Director of the Indiana Sleep Center. His research and clinical practice focuses on the myriad of sleep.
- Low-risk drinking guidelines. (2023). NHS Inform. https://www.nhsinform.scot/healthy-living/alcohol/low-risk-drinking-guidelines/
- Hypothyroidism (underactive thyroid). Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/hypothyroidism/symptoms-causes/syc-2035028
- Sarkola, T., Fukunaga, T., Mäkisalo, H., & Peter Eriksson, C. J. (2000). Acute effect of alcohol on androgens in premenopausal women. Alcohol and alcoholism (Oxford, Oxfordshire), 35(1), 84–90. https://doi.org/10.1093/alcalc/35.1.84
- Turner, R. T., & Sibonga, J. D. (2001). Effects of alcohol use and estrogen on bone. Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 25(4), 276–281.
- Kumar, S., Porcu, P., Werner, D. F., Matthews, D. B., Diaz-Granados, J. L., Helfand, R. S., & Morrow, A. L. (2009). The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. Psychopharmacology, 205(4), 529–564. https://doi.org/10.1007/s00213-009-1562-z
- Hawkins Bressler, L., Bernardi, L. A., De Chavez, P. J., Baird, D. D., Carnethon, M. R., & Marsh, E. E. (2016). Alcohol, cigarette smoking, and ovarian reserve in reproductive-age African-American women. American journal of obstetrics and gynecology, 215(6), 758.e1–758.e9. https://doi.org/10.1016/j.ajog.2016.07.012
- Vigil, P., Meléndez, J., Petkovic, G., & Del Río, J. P. (2022). The importance of estradiol for body weight regulation in women. Frontiers in endocrinology, 13, 951186. https://doi.org/10.3389/fendo.2022.951186
- Khosla, S., Oursler, M. J., & Monroe, D. G. (2012). Estrogen and the skeleton. Trends in endocrinology and metabolism: TEM, 23(11), 576–581. https://doi.org/10.1016/j.tem.2012.03.008
- Emanuele, M. A., Wezeman, F., & Emanuele, N. V. (2002). Alcohol’s effects on female reproductive function. Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 26(4), 274–281.
- Rachdaoui, N., & Sarkar, D. K. (2017). Pathophysiology of the Effects of Alcohol Abuse on the Endocrine System. Alcohol research : current reviews, 38(2), 255–276.
- Dunlavey C. J. (2018). Introduction to the Hypothalamic-Pituitary-Adrenal Axis: Healthy and Dysregulated Stress Responses, Developmental Stress and Neurodegeneration. Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience, 16(2), R59–R60.
- Tin Tin, S., Smith-Byrne, K., Ferrari, P., Rinaldi, S., McCullough, M. L., Teras, L. R., Manjer, J., Giles, G., Le Marchand, L., Haiman, C. A., Wilkens, L. R., Chen, Y., Hankinson, S., Tworoger, S., Eliassen, A. H., Willett, W. C., Ziegler, R. G., Fuhrman, B. J., Sieri, S., Agnoli, C., … Key, T. J. (2024). Alcohol intake and endogenous sex hormones in women: Meta-analysis of cohort studies and Mendelian randomization. Cancer, 130(19), 3375–3386. https://doi.org/10.1002/cncr.35391
- Schrieks, I. C., Heil, A. L., Hendriks, H. F., Mukamal, K. J., & Beulens, J. W. (2015). The effect of alcohol consumption on insulin sensitivity and glycemic status: a systematic review and meta-analysis of intervention studies. Diabetes care, 38(4), 723–732. https://doi.org/10.2337/dc14-1556
- Traversy, G., & Chaput, J. P. (2015). Alcohol Consumption and Obesity: An Update. Current obesity reports, 4(1), 122–130. https://doi.org/10.1007/s13679-014-0129-4
- Low-risk drinking guidelines. (2023). NHS Inform. https://www.nhsinform.scot/healthy-living/alcohol/low-risk-drinking-guidelines/
- Hypothyroidism (underactive thyroid). Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/hypothyroidism/symptoms-causes/syc-2035028
- Sarkola, T., Fukunaga, T., Mäkisalo, H., & Peter Eriksson, C. J. (2000). Acute effect of alcohol on androgens in premenopausal women. Alcohol and alcoholism (Oxford, Oxfordshire), 35(1), 84–90. https://doi.org/10.1093/alcalc/35.1.84
- Turner, R. T., & Sibonga, J. D. (2001). Effects of alcohol use and estrogen on bone. Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 25(4), 276–281.
- Kumar, S., Porcu, P., Werner, D. F., Matthews, D. B., Diaz-Granados, J. L., Helfand, R. S., & Morrow, A. L. (2009). The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. Psychopharmacology, 205(4), 529–564. https://doi.org/10.1007/s00213-009-1562-z
- Hawkins Bressler, L., Bernardi, L. A., De Chavez, P. J., Baird, D. D., Carnethon, M. R., & Marsh, E. E. (2016). Alcohol, cigarette smoking, and ovarian reserve in reproductive-age African-American women. American journal of obstetrics and gynecology, 215(6), 758.e1–758.e9. https://doi.org/10.1016/j.ajog.2016.07.012
- Vigil, P., Meléndez, J., Petkovic, G., & Del Río, J. P. (2022). The importance of estradiol for body weight regulation in women. Frontiers in endocrinology, 13, 951186. https://doi.org/10.3389/fendo.2022.951186
- Khosla, S., Oursler, M. J., & Monroe, D. G. (2012). Estrogen and the skeleton. Trends in endocrinology and metabolism: TEM, 23(11), 576–581. https://doi.org/10.1016/j.tem.2012.03.008
- Emanuele, M. A., Wezeman, F., & Emanuele, N. V. (2002). Alcohol’s effects on female reproductive function. Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 26(4), 274–281.
- Rachdaoui, N., & Sarkar, D. K. (2017). Pathophysiology of the Effects of Alcohol Abuse on the Endocrine System. Alcohol research : current reviews, 38(2), 255–276.
- Dunlavey C. J. (2018). Introduction to the Hypothalamic-Pituitary-Adrenal Axis: Healthy and Dysregulated Stress Responses, Developmental Stress and Neurodegeneration. Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience, 16(2), R59–R60.
- Tin Tin, S., Smith-Byrne, K., Ferrari, P., Rinaldi, S., McCullough, M. L., Teras, L. R., Manjer, J., Giles, G., Le Marchand, L., Haiman, C. A., Wilkens, L. R., Chen, Y., Hankinson, S., Tworoger, S., Eliassen, A. H., Willett, W. C., Ziegler, R. G., Fuhrman, B. J., Sieri, S., Agnoli, C., … Key, T. J. (2024). Alcohol intake and endogenous sex hormones in women: Meta-analysis of cohort studies and Mendelian randomization. Cancer, 130(19), 3375–3386. https://doi.org/10.1002/cncr.35391
- Schrieks, I. C., Heil, A. L., Hendriks, H. F., Mukamal, K. J., & Beulens, J. W. (2015). The effect of alcohol consumption on insulin sensitivity and glycemic status: a systematic review and meta-analysis of intervention studies. Diabetes care, 38(4), 723–732. https://doi.org/10.2337/dc14-1556
- Traversy, G., & Chaput, J. P. (2015). Alcohol Consumption and Obesity: An Update. Current obesity reports, 4(1), 122–130. https://doi.org/10.1007/s13679-014-0129-4